PrepStar制备型液相色谱

PrepStar SD-1 - Analytical to Prep
 
Direct linear scale-up with Star Workstation software for data handling and report generation
Extremely accurate flow rates over wide dynamic ranges with high pressure capabilities for 50, 200, and 500 mL/min pump heads
Pulse-free flow from 0.001 mL/min to 3200 mL/min with five different heads
For production requirements, use LC ReSponder process control software and the PrepStar 530 module

PrepStar 218: Affordable Dedicated Prep
 
Semi-prep capability with 50 or 100 mL/min pump heads
Prep capability with 200 mL/min pump heads at 3500 psi
Star Workstation software for data handling and report generation

PrepStar SD-2 System: Larger Scale Processing at the Benchtop
 
Most economical scale-up format using lower cost, larger particle sorbents
Lower costs with the single pump LPG (Low Pressure Gradient) system option
Process kilograms of sample with up to 800 mL/min flow rates at back pressures up to 2500 psi
Total system control and operational documentation of sample injection, solvent selection, gradient formation, and fraction collection with LC ReSponder
Complete fluid stream control with the PrepStar 530 module
Maximize sample purification and recovery with Varian's unique recycle option

SepTech HPLC: Large-Scale Pharmaceutical Production
 
Purify kg to multi-kg quantities of product with high flow and high back pressure systems and mobile Load & Lock columns up to 600 mm ID
Total operation control and documentation with LC ReSponder software supporting 21 CFR Part 11 compliance
Validate systems and software with optional IQ/OQ documentation
Better manage your separations with UV, density, flow, and pressure monitors
Flexibility and safety with local and remote PC control, as well as explosion-proofed options

PrepStar SD-1 Bio-MPLC: Small Scale Bio-Production
 
Single system for methods development and scale-up
Flow rates from 1 mL/min to 3200 mL/min using 3200 mL pump heads on Varian's industry standard SD-1 pumps
Purify g to kg quantities of biotechnology-based products with a sanitary system that meets cGMP requirements
LC ReSponder software supporting 21 CFR Part 11 compliance and optional IQ/OQ validation protocols
Manage separations using UV, pH, conductivity, and pressure monitors

SepTech Bio-MPLC: Large Scale Bio-Production
 
Purify kg to multi-kg quantities of biotechnology-based products with a medium pressure (MP), sanitary system that meets cGMP requirements
Safety and flexibility with 300 psi rated stainless steel Load & Lock columns and a wide variety of sorbents
LC ReSponder software supporting 21 CFR Part 11 compliance and optional IQ/OQ validation protocols
Manage separations using UV, pH, conductivity, and pressure monitors

Load & Lock: Pack Your Own Preparative and Process Columns
 
Move packed columns, up to 75 mm ID, from the packing station to any location with Axial Compression (AC) maintained by a unique locking mechanism
Preserve bench space by having only the column, not the packing station, in your laboratory
Versatility with AC for normal high-throughput operation or DAC for high efficiency applications up to 200 mm ID
Save time with single-bolt end cap rated up to 2000 psi
Improved separation efficiency with water-jacketed columns

RamPak: Pack Your Own Preparative Columns
 
100/150 mm and 41/77 mm RamPak Systems
Pack columns in minutes with materials best suited for your application
Direct linear scale-up using 5 to 10 μm packing materials
High performance and column longevity with Dynamic Axial Compression (DAC)
For research, use the 41 and 77 mm ID column packing station
For production, use the 100 and 150 mm ID column packing station

From discovery to production

As the leader in preparative chromatography, Varian offers the most complete range of integrated systems to meet research, discovery, and production purification needs. Our turnkey PrepStar and SepTech systems with columns and software provide versatile solutions for applications using semipreparative, preparative, and process chromatography.

Two scale-up formats cover the full spectrum of sample types. High efficiency systems separate complex samples using small particle sorbents (5-10 μm) to deliver milligram to gram quantities of pure product (Scale-Up 1). High-throughput systems use larger particle sorbents (10-25 μm) with column overload strategies to deliver gram to multi-kilogram quantities of pure product in more economical platforms (Scale-Up 2).